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Dietary Flavonoid and Lignan Intake and Gastric Adenocarcinoma Risk in the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study

Fondness for foods packed with flavonoids may shield women from gastric (stomach) cancer.

This study examined whether consuming foods high in flavonoids and lignans can lower the risk of gastric (stomach) cancer. Using validated food frequency questionnaires, researchers collected and evaluated dietary information from 477,312 men and women over a period of 11 years. The gastric cancer (GC) diagnosis status of all the participants was ascertained at the end of the study. 

Researchers discovered that habitual intake of flavonoid from food sources lessened the risk of gastric cancer in women, but not in men. The study concluded that "total dietary flavonoid intake is associated with a significant reduction in the risk of GC in women."

Research Summary Information

  • 2012
  • Raul Zamora-Ros , Antonio Agudo, Leila Luján-Barroso, Isabelle Romieu, Pietro Ferrari, Viktoria Knaze, H Bas Bueno-de-Mesquita, Max Leenders, Ruth C Travis, Carmen Navarro, Emilio Sánchez-Cantalejo, Nadia Slimani, Augustin Scalbert, Veronika Fedirko, Anette Hjartåker, Dagrun Engeset, Guri Skeie, Heiner Boeing, Jana Förster, Kuanrong Li, Birgit Teucher, Claudia Agnoli, Rosario Tumino, Amalia Mattiello, Calogero Saieva, Ingegerd Johansson, Roger Stenling, Maria Luisa Redondo, Peter Wallström, Ulrika Ericson, Kay-Tee Khaw, Angela A Mulligan, Antonia Trichopoulou, Vardis Dilis, Michael Katsoulis, Petra H M Peeters, Lazslo Igali, Anne Tjønneland, Jytte Halkjær, Marina Touillaud, Florence Perquier, Guy Fagherazzi, Pilar Amiano, Eva Ardanaz, Lea Bredsdorff, Kim Overvad, Fulvio Ricceri, Elio Riboli, Carlos A González
  • Unit of Nutrition, Environment, and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, Barcelona, Spain. rzamora@iconcologia.net
  • Yes, Free full text of study was found:
Dietary Flavonoid Intake and the Risk of Digestive...
Citrus fruit intake and gastric cancer: The stomac...

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