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Specific botanical groups of fruit and vegetable consumption and liver cancer and chronic liver disease mortality: a prospective cohort study

Keen consumption of lettuce, carrots, legumes, sweet potatoes, and cruciferous vegetables may guard against the onset of liver cancer and mortality from the disease.

This study compared the liver cancer development and mortality risk between consumers and non-consumers of specific fruits and vegetables. Researchers tracked the eating habits, rate of occurrence, and mortality from liver cancer among 485,403 middle-aged and elderly men and women recruited from the National Institutes of Health-American Association of Retired Persons Diet and Health Study. 

Researchers observed that eating generous portions of lettuce, carrots, legumes, sweet potatoes, and cruciferous vegetables drove down the risk of developing and dying from liver cancer. The findings of this study showed that liver cancer is less likely to occur among high consumers of vegetables, such as lettuce, carrots, legumes, sweet potatoes, and cruciferous vegetables.

Research Summary Information

  • 2023
  • Longgang Zhao, Lina Jin, Jessica L Petrick, Hongmei Zeng, Fenglei Wang, Li Tang, Stephanie A Smith-Warner, A Heather Eliassen, Fang Fang Zhang, Peter T Campbell, Edward Giovannucci, Linda M Liao, Katherine A McGlynn, Susan E Steck, Xuehong Zhang
  • Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Slone Epidemiology Center, Boston University, Boston, MA, USA. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: xuehong.zhang@channing.harvard.edu.
  • No, Free full text of study was not found.
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