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Long-term association of vegetable and fruit intake with risk of dementia in Japanese older adults: the Hisayama study

Generous consumption of vegetables may hinder the development of dementia and Alzheimer's disease in older men and women.

This study quantified the risk of dementia and Alzheimer's disease among older men and women on high fruit and vegetable diet. Out of the 1,071 Japanese men and women aged 60 years and above who took part in this study, 464 of them developed dementia and Alzheimer's disease over a follow-up period of 24 years.

Researchers observed that the odds of developing dementia and Alzheimer's disease decreased by 27% and 31% respectively among participants who consumed the highest amounts of vegetables. This study supports increased intake of vegetables as a dietary strategy for the prevention of dementia and Alzheimer's disease.

Research Summary Information

  • 2022
  • Yasumi Kimura , Daigo Yoshida, Tomoyuki Ohara, Jun Hata, Takanori Honda, Yoichiro Hirakawa, Mao Shibata, Emi Oishi, Satoko Sakata, Yoshihiko Furuta, Sanmei Chen, Kazuhiro Uchida, Tomohiro Nakao, Takanari Kitazono, Toshiharu Ninomiya
  • Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. yoshidad@college.fdcnet.ac.jp. Division of Community Health and Home Care Nursing, Department of Nursing, Faculty of Nursing, Fukuoka Nursing College, Fukuoka, Japan. yoshidad@college.fdcnet.ac.jp. Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Department of Global Health Nursing, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. Department of Nutritional Sciences, Nakamura Gakuen University, Fukuoka, Japan.
  • Yes, Free full text of study was found:
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