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Association Between Lifetime Marijuana Use and Cognitive Function in Middle Age: CARDIA Study

Regular use of marijuana during adolescence and young adulthood may lead to a decline in cognitive function in midlife.

This study looked at the impact of long-term use of marijuana on cognitive function in middle-aged individuals. A total of 5,115 men and women took part in this study and their marijuana smoking habits and cognitive performance were assessed over a 25-year period. 

Researchers discovered that the use of marijuana during adolescence and young adulthood heightened the risk of suffering from cognitive impairment in middle age. This study strengthened the evidence that repeated exposure to marijuana for a long time may have a detrimental effect on cognitive function in middle-aged men and women.

Research Summary Information

  • 2016
  • Reto Auer, Eric Vittinghoff, Kristine Yaffe, Arnaud Künzi, Stefan G Kertesz, Deborah A Levine, Emiliano Albanese, Rachel A Whitmer, David R Jacobs Jr, Stephen Sidney, M Maria Glymour, Mark J Pletcher
  • Department of Epidemiology and Biostatistics, University of California-San Francisco2Department of Ambulatory Care and Community Medicine, University of Lausanne, Lausanne, Switzerland. Department of Epidemiology and Biostatistics, University of California-San Francisco. Department of Epidemiology and Biostatistics, University of California-San Francisco3Department of Psychiatry and Neurology, University of California-San Francisco. Department of Ambulatory Care and Community Medicine, University of Lausanne, Lausanne, Switzerland. Center for Surgical Medical and Acute Care Research, Birmingham Veterans Affairs Medical Center, Birmingham, Alabama5Department of Medicine, University of Alabama at Birmingham School of Medicine. Department of Internal Medicine, University of Michigan Medical School, Ann Arbor7Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan8Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor9Department of. Department of Psychiatry, University of Geneva, Geneva, Switzerland. Kaiser Permanente Division of Research, Oakland, California. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis.
  • Yes, Free full text of study was found:
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