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Smoking, alcohol consumption and risk of Dupuytren's disease: a Mendelian randomization study
An individual's love for alcohol may make him/her highly prone to suffering from Dupuytren's disease.
Dupuytren's disease (DD), also known as Dupuytren's contracture, Viking disease, or palmar fibromatosis, is a condition that results in progressive thickening and tightening of the tissues under the palm, making the fingers to bend towards the palm. This study investigated if cigarette smoking and alcohol drinking is tied to the occurrence of Dupuytren's disease. Researchers matched smoking and alcohol intake habits with Dupuytren's disease diagnosis status in a large number of participants.
Researchers found out that participants in the alcohol consumption group tend to have elevated risk of developing Dupuytren's contracture. "This is the first study to prove that drinking alcohol could cause DD.," the authors noted.
Research Summary Information
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2023
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Zifeng Wang, Zhenyu Wang, Zijian Yan, Zhujie Xu, Aiguo Gao
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Department of Orthopedics, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, 214000, China. Department of Orthopedics, Taicang Shaxi People's Hospital, Taicang, 215400, China. The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. Department of Orthopedics, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, 214000, China. jsxuzhujie@163.com. Department of Orthopedics, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, 214000, China. gaoaiguo899@163.com.
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