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Ultra-processed foods and mortality: analysis from the Prospective Urban and Rural Epidemiology study

The odds of dying prematurely from cardiovascular ailments and other chronic diseases may be stacked against generous consumers of ultra-processed foods.

The purpose of this study was to determine the relationship between likeness for ultra-processed foods and total mortality risk. Researchers followed over 130,000 men and women residing in 5 different continents for an average of 10.2 years, monitoring their dietary choices and death records. 

Researchers observed a high death toll from both cardiovascular and non-cardiovascular diseases among lovers of ultra-processed foods. The results of this study indicate that diets that encourage the consumption of ultra-processed foods may be a major contributing factor to the rising number of deaths from chronic diseases and other causes.

Research Summary Information

  • 2023
  • Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan, Viswanathan Mohan, Sumathi Swaminathan, Alvaro Avezum, Scott A Lear, Annika Rosengren, Paul Poirier, Fernando Lanas, Patricio Lopez-Jaramillo, Biju Soman, Chuangshi Wang, Andrés Orlandini, Noushin Mohammadifard, Khalid F AlHabib, Jephat Chifamba, Afzal Hussein Yusufali, Romaina Iqbal, Rasha Khatib, Karen Yeates, Thandi Puoane, Yuksel Altuntas, Homer Uy Co, Sidong Li, Weida Liu, Katarzyna Zatońska, Rita Yusuf, Noorhassim Ismail, Victoria Miller, Salim Yusuf; Prospective Urban Rural Epidemiology (PURE) study investigators
  • Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. Electronic address: mahshid.dehghan@phri.ca. Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. Dr. Mohan's Diabetes Specialities Centre, Chennai, India. St John's Research Institute, St John's National Academy of Health Sciences, Sarjapur Road, Koramangala, Bangalore, Karnataka, India. International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil. Faculty of Health Sciences, Simon Fraser University c/o Healthy Heart Program, St. Paul's Hospital, Vancouver, British Columbia, Canada. Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, VGR Region, Sweden. Heart and Lung Institute, Laval University, Quebec City, QC, Canad. University of La Frontera, Temuco, Chile. Masira Research Institute, Medical School, Universidad de Santander, Bucaramanga, Colombia. Health Action by People, Thiruvananthapuram, Kerala, India. Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China. Clinical Studies Latin America, Rosario, Santa Fe, Argentina. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia. University of Zimbabwe, Faculty of Medicine and Health Sciences, Unit of Physiology, Harare, Zimbabwe. Hatta Hospital, Dubai Medical College, Dubai Health Authority, Dubai, United Arab Emirates. Department of Community Health Sciences and Medicine, Aga Khan University, Pakistan. Institute for Community and Public Health, Birzeit University, Birzeit, Palestine & Advocate Research Institute, Advocate Health Care, IL, USA. Department of Medicine, Queen's University, Kingston, Canada. School of Public Health, University of the Western Cape, Bellville, South Africa. University of Health Sciences Turkey, Faculty of Medicine, Istanbul Sisli Hamidiye Etfal Training and Research Hospital, Clinic of Endocrinology and Metabolism, Sisli, Istanbul, Turkey. University of the Philippines College of Medicine, Manila, Philippines. Social Medicine Department of Wroclaw Medical University, Poland. Independent University, Dhaka, Bangladesh. Department of Community Health, Faculty of Medicine, University Kebangsaan, Kuala Lumpur, Malaysia.
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