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An increase in the risk of having spontaneous abortion and low birth weight babies is associated with high intake of caffeine-containing beverages during pregnancy.
Miscarriage is more likely to occur in women who consume coffee and caffeine products during pregnancy.
Caffeine intake is associated with increased blood pressure and decreased forearm blood flow during dynamic exercise.
Caffeine may promote arterial stiffness and high blood pressure in the aorta and brachial artery.
Caffeine and caffeinated beverages may either increase or decrease serum estradiol concentrations in healthy premenopausal women, apparently depending on the race.