Dietary flavonols intake and risk of esophageal and gastric cancer: a meta-analysis of epidemiological studies.

Low esophageal and gastric cancer risk is associated with generous intake of diets high in flavonols.

This study investigated the correlation between regular intake of flavonol-rich diets and the odds of developing esophageal and gastric (stomach) cancer by meta-analysis. Twenty studies that examined 523,971 subjects and 4593 gastric and esophageal cancer cases were included in this meta-analysis. Researchers observed a low incidence of gastric and esophageal cancer among subjects, particularly women and smokers, who regularly consumed diets containing high amounts of flavonols. The findings of this meta-analysis reveal that high intake of flavonol-rich foods may confer significant protection against stomach and esophageal cancer.

Research Summary Information

  • 2016
  • Xie Y, Huang S, Su Y
  • Stem Cell Biology and Therapy Laboratory, Lab medicine of Maternity and Child Care Hospital of Yubei District, Ministry of Education Key Laboratory of Child Development and Disorders, the Children's Hospital of Chongqing Medical University, Chongqing 400014, China. xieyan1st@gmail.com. Orthopedic Department II, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, the Children's Hospital of Chongqing Medical University, Chongqing 400014, China. huangshifeng09@163.com. Orthopedic Department II, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, the Children's Hospital of Chongqing Medical University, Chongqing 400014, China. yuxisu@163.com.
  • Yes, Free full text of study was found:
  • No source of funding disclosure found
  • No potential conflicts disclosure found
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