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Red meat intake, insulin resistance, and markers of endothelial function among Iranian women

High red meat intake may increase serum concentrations of insulin, glucose, and endothelial dysfunction biomarkers.

This research work was carried out to determine the effect of red meat on insulin resistance and endothelial function. Using a validated food frequency questionnaire, researchers monitored the diet of 420 healthy female nurses in Ishfahan, Iran. The glycemic indexes and plasma concentrations of insulin and adhesion molecules of all the subjects were constantly measured throughout the entire duration of the study.

Researchers found out that subjects who consumed large quantities of red meat had high serum concentrations of insulin, glucose, and adhesion molecules, such as E-selectin, soluble vascular cell adhesion molecule-1 (sVCAM-1), and soluble intercellular adhesion molecule-1 (sICAM-1). These findings show that high consumption of red meat is associated with endothelial dysfunction, increased insulin resistance, and abnormal glucose metabolism.

Research Summary Information

  • 2014
  • Farzaneh Barak, Ebrahim Falahi, Ammar Hassanzadeh Keshteli, Ahmadreza Yazdannik, Parvane Saneei and Ahmad Esmaillzadeh
  • Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Yes, Free full text of study was found:
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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