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BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis.

Obese and overweight men may have greater risk of developing azoospermia and oligozoospermia.

This study investigated the association of body mass index (BMI) with sperm count. Researchers conducted a systematic review and meta-analysis on standardized data obtained from 21 studies encompassing 13077 men. The BMI and sperm count of all the subjects were assessed.

Researchers observed a J-shaped relationship between BMI categories and oligozoospermia and azoospermia. A greater incidence of azoospermia and oligozoospermia were found in overweight and obese men than in underweight and normal weight men. The findings of this analysis show that weight gain promotes the development of azoospermia and oligozoospermia in males.

Research Summary Information

  • 2013
  • Sermondade N1, Faure C, Fezeu L, Shayeb AG, Bonde JP, Jensen TK, Van Wely M, Cao J, Martini AC, Eskandar M, Chavarro JE, Koloszar S, Twigt JM, Ramlau-Hansen CH, Borges E Jr, Lotti F, Steegers-Theunissen RP, Zorn B, Polotsky AJ, La Vignera S, Eskenazi B, Tremellen K, Magnusdottir EV, Fejes I, Hercberg S, Lévy R, Czernichow S.
  • Service d'Histologie-Embryologie-Cytogénétique-CECOS, Hôpital Jean Verdier (AP-HP), Bondy, France.
  • Yes, Free full text of study was found:
  • Yes. Source of funding disclosure found
  • J..E.C. was supported in part by National Institute of Diabetes and Digestive and Kidney Diseases grant 5P30DK046200-19 and B.E. was supported in part by National Institutes of Health grant P42ES04705.
  • No. Potential conflicts disclosure not found
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