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Association Between Androgen Deprivation Therapy Use and Diagnosis of Dementia in Men With Prostate Cancer.

Prostate cancer patients on androgen deprivation therapy may have a high tendency to suffer from dementia.

​This study evaluated the relationship between the use of androgen deprivation drugs and the subsequent development of dementia in prostate cancer patients. Researchers followed more than 150,000 elderly men diagnosed with prostate cancer for at least 10 years, monitoring the use of androgen deprivation drugs and prevalence of dementia in the study population. 

Researchers observed that the probability of a prostate cancer patient developing dementia rose with the intake of androgen deprivation drugs. The findings of this study demonstrate that androgen deprivation therapy may put a prostate cancer patient at high risk of having dementia.

Research Summary Information

  • 2019
  • Jayadevappa R, Chhatre S, Malkowicz SB, Parikh RB, Guzzo T, Wein AJ
  • Leonard Davis Institute of Health Economics, Perlman School of Medicine, University of Pennsylvania, Philadelphia. Perlman School of Medicine, Division of Urology, Department of Surgery, University of Pennsylvania, Philadelphia. Perlman School of Medicine, Department of Medicine, University of Pennsylvania, Philadelphia. Perlman School of Medicine, Department of Psychiatry, University of Pennsylvania, Philadelphia.
  • Yes, Free full text of study was found:
Association Between Androgen Deprivation Therapy a...

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