when I read your letter, I thought you were writing about me!  LOL!  Hypothyroid, Celiac disease, Barrett's Esophagus, Psoriatic Arthritis, chronic anemia, etc.   I had been taking ppi pills for over 20 years!  It was not until I broke 6 bones, shrank 3 inches, and developed very painful compression fractures on my spine, as well as several hospitalizations for aspiration pneumonia that I had enough!  I had found the McDougall plan, which I followed, but the problems were just too far gone.  I finally had a Nissen fundoplication and hiatal hernia repair 18 months ago and have never looked back or taken another pill.   I realize that is a drastic step but it has been a game changer.  I feel good, and no longer take meds for my psoriatic arthritis either (methotrexate and Enbrel).  I still have pain from the fractures and arthritis, but it is manageable without meds. I still follow McDougall, etc and generally feel ok except for inability to lose weight after my initial 30lb loss.  Hope you are feeling well these days!!