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Use of Antihypertensive Drugs and Risk of Malignant Melanoma: A Meta-analysis of Observational Studies.

Individuals taking antihypertensive drugs in the class of diuretics and beta-blockers may have a high predisposition to skin cancer.

​The purpose of this study was to undertake a meta-analysis on the relationship between the usage of antihypertensive drug and the probability of developing malignant melanoma—a form of skin cancer. A total of 8 studies were included in this meta-analysis. 

Researchers found out that the tendency for malignant melanoma to occur was high among users of antihypertensive drugs belonging to the class of diuretics and beta-blockers. In conclusion, a significant increase in the risk of malignant melanoma was found among individuals on diuretics and beta-blocking agents in this study.

Research Summary Information

  • 2018
  • Tang H, Fu S, Zhai S, Song Y, Han J.
  • Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, 1050 Wishard Blvd, Indianapolis, IN, 46202, USA. Center for Pharmacoepidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA. Department of Pharmacy, Peking University Third Hospital, Beijing, China. School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA. Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, 1050 Wishard Blvd, Indianapolis, IN, 46202, USA. jialhan@iu.edu. Center for Pharmacoepidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA. jialhan@iu.edu. Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA. jialhan@iu.edu.
  • No, Free full text of study was not found.
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