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Antidepressant use and 10-year incident fracture risk: the population-based Canadian Multicentre Osteoporosis Study (CaMoS).

Individuals on antidepressants may have a high tendency of breaking a bone.

​This study was carried out to determine the risk of fracture associated with the use of anti-depressant medications. Researchers followed 6,645 Canadian men and women for 10 years, monitoring their usage of anti-depressants and the incidence of fracture. 

Researchers discovered that antidepressant users were more prone to experience fragility fracture than non-users of these drugs. This study strengthens the body of evidence implicating antidepressant use as a contributing factor to the occurrence of fracture.

Research Summary Information

  • 2014
  • Moura C, Bernatsky S, Abrahamowicz M, Papaioannou A, Bessette L, Adachi J, Goltzman D, Prior J, Kreiger N, Towheed T, Leslie WD, Kaiser S, Ioannidis G, Pickard L, Fraser LA, Rahme E.
  • McGill University, Montreal, Canada, cristiano.soaresdemoura@mail.mcgill.ca.
  • Yes, Free full text of study was found:
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