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Antidepressant use during pregnancy and risk of autism spectrum disorder in children.

The use of antidepressant medications during pregnancy may heighten the risk of having offspring with autism spectrum disorder.

​This study investigated the link between maternal use of antidepressants during pregnancy and the odds of having babies with autism spectrum disorder (ASD). Researchers evaluated more than 145,000 pregnant women between 1998 and 2009. The offspring of these women were followed for an average of 6 years.

Researchers found out that women who took antidepressants, especially medications that belong to the class of selective serotonin re-uptake inhibitor (SSRIs), in the second and third trimester of pregnancy had high propensity of giving birth to children with autism. The results of this study suggest that maternal use of antidepressants during pregnancy may be a risk factor for autism spectrum disorder .

Research Summary Information

  • 2016
  • Boukhris T, Sheehy O, Mottron L, Bérard A.
  • Faculty of Pharmacy, University of Montréal, Montréal, Québec, Canada2Research Unit on Medications and Pregnancy, Research Center, CHU Sainte-Justine, Montréal, Québec, Canada. Research Unit on Medications and Pregnancy, Research Center, CHU Sainte-Justine, Montréal, Québec, Canada. Centre d'excellence en Troubles Envahissants du Développement de l'Université de Montréal, Montréal, Québec, Canada4Département de Psychiatrie, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada5Centre de Recherche de l'Institut Universitaire de Psych.
  • Yes, Free full text of study was found:
Antidepressant use during pregnancy and the risk o...
Maternal SSRIs experience and risk of ASD in offsp...

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