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Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries in Prospective Urban and Rural Epidemiology study: prospective cohort study

The odds of developing and dying from cardiovascular disease may be stacked against habitual consumers of generous portions of refined grains.

This study analyzed the connection between the intake of cereal grains and cardiovascular disease development and mortality risk. A group of international researchers reviewed the nutritional and medical data of more than 140,000 men and women recruited from 21 countries. 

Researchers discovered that consumers of more than 7 servings of refined grains per day experienced an upsurge in cardiovascular disease and mortality risk compared to their counterparts who ate little or none of these foods. The data from this study indicate that lovers of refined grains may be highly prone to acquiring and dying from cardiovascular disease.

Research Summary Information

  • 2021
  • Sumathi Swaminathan, Mahshid Dehghan, John Michael Raj, Tinku Thomas, Sumathy Rangarajan, David Jenkins, Prem Mony, Viswanathan Mohan, Scott A Lear, Alvaro Avezum, Patricio Lopez-Jaramillo, Annika Rosengren, Fernando Lanas, Khalid F AlHabib, Antonio Dans, Mirac Vural Keskinler, Thandi Puoane, Biju Soman, Li Wei, Katarzyna Zatonska, Rafael Diaz, Noorhassim Ismail, Jephat Chifamba, Roya Kelishadi, Afzalhussein Yusufali, Rasha Khatib, Liu Xiaoyun, Hu Bo, Romaina Iqbal, Rita Yusuf, Karen Yeates, Koon Teo, Salim Yusuf
  • St John's Research Institute, Bangalore, India. Population Health Research Institute (PHRI), McMaster University, Hamilton Health Sciences, Hamilton, ON, Canada Mahshid.dehghan@phri.ca. St John's Medical College, Bangalore, India. Population Health Research Institute (PHRI), McMaster University, Hamilton Health Sciences, Hamilton, ON, Canada. Department of Nutritional Sciences and Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Madras Diabetes Research Foundation and Dr Mohan's Diabetes Specialities Centre, Chennai, India. Faculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada. International Research Centre, Hospital Alemao Oswaldo Cruz, Sao Paulo, Brazil, Universidade Santo Amaro (UNISA), Sao Paulo, Brazil. Masira Research Institute, Medical School, Santander University (UDES), Colombia. Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Sahlgrenska University Hospital, Gothenburg, Sweden. Universidad de La Frontera, Temuco, Chile. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia. University of Philippines, Section of Adult Medicine and Medical Research Unit, Manila, Philippines. Department of Internal Medicine, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey. University of the Western Cape, Bellville, South Africa. Health Action by People, Thiruvananthapuram, Kerala, India. Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India. National Centre for Cardiovascular Diseases, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China. Wroclaw Medical University, Department of Social Medicine, Wroclaw, Poland. Estudios Clinicos Latinoamerica ECLA, Rosario, Santa Fe, Argentina. Department of Community Health, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur, Malaysia. Physiology Department, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran. Dubai Medical University, Hatta Hospital, Dubai Health Authority, Dubai, United Arab Emirates. Institute for Community and Public Health, Birzeit University, Birzeit, Palestine. Advocate Research Institute, Advocate Health Care, Illinois, USA. Departments of Community Health Sciences and Medicine, Aga Khan University, Karachi, Pakistan. School of Life Sciences, Independent University, Bangladesh, Dhaka, Bangladesh. Department of Medicine, Queen's University, Kingston, ON, Canada. New York University, College of Global Public Health, NY, USA.
  • Yes, Free full text of study was found:
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