A significant reduction in insulin sensitivity may be found in healthy individuals who consumed caffeine regularly.

​Insulin resistance is the hallmark of type 2 diabetes. This study evaluated the impact dietary intake of caffeine has on insulin sensitivity in healthy persons. Researchers compiled data obtained from 7 randomized control trials (RCTs).

After analysis of the data, researchers discovered that caffeine consumption resulted in significant decrease in insulin sensitivity. This meta-analysis supports the hypothesis that regular dietary exposure to caffeine may put a healthy individual on the path to having insulin resistance.