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Parental alcohol consumption and risk of leukemia in the offspring: a systematic review and meta-analysis.

Maternal consumption of alcohol, including wine, during pregnancy may increase the risk of having offspring with acute myeloid leukemia.

​This meta-analysis evaluated the effect of parental consumption of alcohol on the risk of leukemia in their children. Researchers compiled data from 39 studies involving 16,000 patients with leukemia and 30,000 healthy children. 

Researchers noted that maternal intake of alcohol, including wine, correlated with rising risk of acute myeloid leukemia (AML) in their offspring. This study suggests that women who consumed alcohol during pregnancy may likely give birth to children with high chances of developing acute myeloid leukemia.

Research Summary Information

  • 2017
  • Karalexi MA, Dessypris N, Thomopoulos TP, Ntouvelis E, Kantzanou M, Diamantaras AA, Moschovi M, Baka M, Hatzipantelis E, Kourti M, Polychronopoulou S, Stiakaki E, Mora AM, Wunsch-Filho V, Infante-Rivard C, Loutradis D, Petridou ET.
  • Department of Hygiene, Epidemiology and Medical Statistics First Department of Obstetrics and Gynecology, School of Medicine, University of Athens Haematology-Oncology Unit, First Department of Pediatrics, Athens University Medical School, 'Aghia Sophia' Children's Hospital Department of Pediatric Hematology-Oncology, 'Pan. & Agl. Kyriakou' Children's Hospital Department of Pediatric Haematology-Oncology, 'Aghia Sophia' Children's Hospital, Athens 2nd Department of Pediatrics, Aristotelion University of Thessaloniki, AHEPA General Hospital Department of Pediatric Hematology and Oncology, Hippokration Hospital, Thessaloniki Department of Pediatric Hematology-Oncology, University Hospital of Heraklion, Heraklion, Greece Program Medical Neurosciences, Charité-Medicine University, Berlin, Germany Central American Institute for Studies on Toxic Substances, National University, Heredia, Costa Rica Faculty of Public Health, University of Sao Paulo, Sao Paulo, Brazil Department of Epidemiology, Biostatistics, and Occupational Health, Faculty of Medicine, McGill University, Montre[Combining Acute Accent]al, Que[Combining Acute Accent]bec, Canada.
  • No, Free full text of study was not found.
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