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Lifetime and baseline alcohol intakes and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition study.

Regular drinking of alcohol may trigger the development of pancreatic cancer.

​This study evaluated the impact of alcohol consumption on the risk of pancreatic cancer. Researchers tracked the rate of alcohol intake and pancreatic cancer diagnosis among over 475,000 men and women for 14 years. 

The research team discovered the higher the frequency and duration of alcohol consumption, the greater a participant's risk of developing pancreatic cancer. The results of this study support a positive association between alcohol intake and increased likelihood of pancreatic cancer.

Research Summary Information

  • 2018
  • Naudin S, Li K, Jaouen T, Assi N, Kyrø C, Tjønneland A, Overvad K, Boutron-Ruault MC, Rebours V, Védié AL, Boeing H, Kaaks R, Katzke V, Bamia C, Naska A, Trichopoulou A, Berrino F, Tagliabue G, Palli D, Panico S, Tumino R, Sacerdote C, Peeters PH, Bueno-de-Mesquita HBA, Weiderpass E, Gram IT, Skeie G, Chirlaque MD, Rodríguez-Barranco M, Barricarte A, Quirós JR, Dorronsoro M, Johansson I, Sund M, Sternby H, Bradbury KE, Wareham N, Riboli E, Gunter M, Brennan P, Duell EJ, Ferrari P.
  • Nutritional Methodology and Biostatistics Group, International Agency for Research on Cancer, Lyon, France. Danish Cancer Society Research Center, Copenhagen, Denmark. Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark. CESP, INSERM U1018, University of Paris-Sud, UVSQ, University of Paris-Saclay, Villejuif, France. Institut Gustave Roussy, Villejuif, France. Pancreatology Unit, Beaujon Hospital, Clichy, France. INSERM U1149, University Paris 7, Paris, France. Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Potsdam, Germany. Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Hellenic Health Foundation, Athens, Greece. Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, WHO Collaborating Center for Nutrition and Health, National and Kapodistrian University of Athens, Athens, Greece. Department of Preventive & Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Lombardy Cancer Registry Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Cancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. Department of Clinical and Experimental Medicine, University Federico II, Naples, Italy. Cancer Registry and Histopathology Department, Civic M.P.Arezzo Hospital, Ragusa, Italy, Ragusa, Italy. Unit of Cancer Epidemiology, Hospital and Center for Cancer Prevention (CPO), Città della Salute e della Scienza University, Turin, Italy. Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands. Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom. Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala, Malaysia, Lumpur. Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway. Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. 25 Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland. 26 Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia, Spain. 27 CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain. 28 Department of Health and Social Sciences, University of Murcia, Murcia, Spain. 29 Biosanitary Investigation Institute (IBS) of Granada, University Hospital and University of Granada, Granada, Spain. 30 Navarra Public Health Institute, Pamplona, Spain. 31 Navarra Institute for Health Research (IdiSNA), Pamplona, Spain. 32 Public Health Directorate, Asturias, Spain. 33 Subdirección de Salud Pública de Gipuzkoa, Gobierno Vasco, San Sebastian, Spain. 34 Department of Odontology, Cariology, Umeå University, Umeå, Sweden. 35 Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden. 36 Department of Surgery, Institution of Clinical Sciences Malmö, Lund University, Malmö, Sweden. 37 Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. 38 MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, United Kingdom. 39 School of Public Health, Imperial College London, London, United Kingdom. 40 Nutrition and Epidemiology Group, International Agency for Research on Cancer, Lyon, France. 41 Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France. 42 Unit of Nutrition and Cancer, Catalan Institute of Oncology (ICO-Idibell), Barcelona, Spain.
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