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Statin use and risk of new-onset diabetes: a meta-analysis of observational studies.

Individuals taking statins may have increased likelihood of developing type 2 diabetes.

Statins are a group of medications administered to patients to lower their blood cholesterol levels. This study investigated the relationship between statin use and type 2 diabetes risk. Researchers systematically reviewed data obtained from 20 studies that examined over 1,000 subjects.

The team of investigators found out that statin intake elevated the risk of developing type 2 diabetes by 44%. The diabetes-promoting effect of statins was found to be increase with higher dosages and longer usage. The findings of this meta-analysis suggest that individuals who take statins are highly vulnerable to type 2 diabetes mellitus.

Research Summary Information

  • 2017
  • M. Casula, PhD, , ,F. Mozzanica, PharmD, L. Scotti, PhD, E. Tragni, PhD, A. Pirillo, PhDc, G. Corrao (Professor), A.L. Catapano (Professor)
  • Epidemiology and Preventive Pharmacology Centre (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, via Balzaretti 9, 20133 Milan, Italy Department of Statistics and Quantitative Methods, Division of Biostatistics, Epidemiology and Public Health, University of Milano-Bicocca, Via Bicocca degli Arcimboldi 8, 20126 Milan, Italy Center for the Study of Atherosclerosis, E. Bassini Hospital, Via M. Gorki 50, Cinisello Balsamo, 20092 Milan, Italy IRCCS MultiMedica, via Milanese 300, 20099 Sesto S. Giovanni (MI), Italy
  • No, Free full text of study was not found.
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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