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Effects of selective serotonin reuptake inhibitors on glaucoma: A nationwide population-based study.

Habitual intake of selective serotonin reuptake inhibitors (SSRIs) is tied to a high risk of having glaucoma.

​This study assessed whether patients with depression treated with antidepressants belonging to the class selective serotonin reuptake inhibitors (SSRIs) were at risk of developing glaucoma. The study population comprised of over 100,000 men and women recruited from Taiwan's National Health Insurance Research Database. 

Researchers discovered that the use of selective serotonin reuptake inhibitors correlated with increased risk of glaucoma. This study provides evidence that depressive patients treated with selective serotonin reuptake inhibitors may have a high tendency of being diagnosed with glaucoma.

Research Summary Information

  • 2017
  • Chen VC, Ng MH, Chiu WC, McIntyre RS, Lee Y, Lin TY, Weng JC, Chen PC, Hsu CY.
  • Department of Psychiatry, Chang Gung Medical Foundation, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan. Department of Psychiatry, School of Medicine, Chang Gung University, Taoyuan, Taiwan. Tsaotun Psychiatric Center, Ministry of Health and Welfare, Nan-Tou County, Taiwan. PhD Student of Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan. Department of Psychiatry, Cathay General Hospital, Taipei, Taiwan. College of Medicine, Fu Jen Catholic University, Taipei, Taiwan. Mood Disorders Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Canada. Departments of Psychiatry and Pharmacology, University of Toronto, Toronto, Canada. Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan. Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei, Taiwan. Department of Neurology, Kaoshiung Medical University Hospital, Kaoshiung, Taiwan. Department of Environmental and Occupational Medicine, National Taiwan University Hospital, Taipei, Taiwan.
  • Yes, Free full text of study was found:
Use of selective serotonin reuptake inhibitors and...
Selective serotonin reuptake inhibitor treatment a...

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