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Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women

High dietary exposure to flavonoids may help curb cognitive decline in men and women.

This research work studied how long-term consumption of flavonoid-rich foods affects cognitive function in men and women. Researchers collected and collated data on the eating habits and incidence of cognitive decline among more than 65,000 health professionals from the United States. 

Researchers identified a protective association between high flavonoid diet and cognitive decline. This study concluded that eating flavonoid-containing foods regularly may help prevent cognitive decline in men and women.

Research Summary Information

  • 2021
  • Tian-Shin Yeh, Changzheng Yuan, Alberto Ascherio, Bernard A Rosner, Walter C Willett, Deborah Blacker
  • From the Departments of Epidemiology (T.-S.Y., A.A., W.W., D.B.), Nutrition (T.-S.Y., A.A., W.W., C.Y.), and Biostatistics (B.R.), Harvard T.H. Chan School of Public Health, Harvard University; Channing Division of Network Medicine (T.-S.Y., A.A., W.W., C.Y., B.R.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; School of Public Health (C.Y.), Zhejiang University, Hangzhou, China; Department of Medicine (B.R.), Harvard Medical School; and Department of Psychiatry (D.B.), Massachusetts General Hospital, Harvard Medical School, Boston. From the Departments of Epidemiology (T.-S.Y., A.A., W.W., D.B.), Nutrition (T.-S.Y., A.A., W.W., C.Y.), and Biostatistics (B.R.), Harvard T.H. Chan School of Public Health, Harvard University; Channing Division of Network Medicine (T.-S.Y., A.A., W.W., C.Y., B.R.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; School of Public Health (C.Y.), Zhejiang University, Hangzhou, China; Department of Medicine (B.R.), Harvard Medical School; and Department of Psychiatry (D.B.), Massachusetts General Hospital, Harvard Medical School, Boston. walter.willett@channing.harvard.edu.
  • Yes, Free full text of study was found:
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