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Dietary Flavonoid and Lignan Intake and Mortality in Prospective Cohort Studies: Systematic Review and Dose-Response Meta-Analysis

Individuals on high flavonoid diets may have low chances of suffering from deaths arising from cardiovascular diseases and other causes.

This meta-analysis determined how the ingestion of foods high in flavonoids and lignans affects cardiovascular and all-cause (total) mortality risk. Researchers pooled data and evidence from 22 eligible studies. 

Researchers discovered that the higher the amounts and frequency of consumption of foods rich in flavonoids, the lower the likelihood of dying from cardiovascular diseases, and other ailments. Daily dietary intake of an additional 100 mg of flavonoids was found to cut down cardiovascular and total mortality risk by as much as 4% and 6% respectively. "Findings from this meta-analysis indicated that dietary flavonoids are associated with decreased risk of all-cause and CVD mortality," the researchers concluded.

Research Summary Information

  • 2017
  • Giuseppe Grosso , Agnieszka Micek, Justyna Godos, Andrzej Pajak, Salvatore Sciacca, Fabio Galvano , Edward L Giovannucci
  • NNEdPro Global Centre for Nutrition and Health, Saint John's Innovation Centre, Cambridge, United Kingdom. Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, Azienda Ospedaliera Policlinico-Universitaria, Catania, Italy. Department of Epidemiology and Population Studies, Jagiellonian University Medical College, Krakow, Poland. Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy. Department of Epidemiology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts. Department of Nutrition, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Yes, Free full text of study was found:
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