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Increased dietary and circulating lycopene are associated with reduced prostate cancer risk: a systematic review and meta-analysis.

​Marked reduction in the risk of prostate cancer is associated with high consumption and elevated plasma concentrations of lycopene.

This study was carried out to determine the effect of high serum levels and increased dietary intake of lycopene on the risk of developing prostate cancer. Researchers collated and analyzed data on the blood levels and dietary lycopene consumption rates of 692,012 subjects and the incidence of prostate cancer in the study population.

The team of investigators discovered a significant protective association between high dietary and circulating levels of lycopene and prostate cancer risk. The incidence of prostate cancer was found to decrease by 1% for every extra 1mg of lycopene consumed and 3.5-3.6% for every additional 10ug/dl increase in the serum concentrations of lycopene. However, both dietary and circulating lycopene was found to have no effect on advanced prostate cancer in this study. The results of this study show that generous intake of foods high in lycopene may help reduce an individual's likelihood of developing prostate cancer.

Research Summary Information

  • 2017
  • Rowles JL 3rd, Ranard KM, Smith JW, An R, Erdman JW Jr
  • Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
  • Yes, Free full text of study was found:
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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