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Effects of Vitamin and Antioxidant Supplements in Prevention of Bladder Cancer: a Meta-Analysis of Randomized Controlled Trials.

Beta-carotene supplements may increase bladder cancer risk.

This study assessed the role of vitamin and antioxidant supplements play in the prevention of bladder cancer by meta-analysis. Researchers conducted a meticulous meta-analysis on data obtained from fourteen (14) randomized controlled trials.

The team of investigators observed that beta carotene supplements increased the odds of developing bladder cancer. In addition, other vitamin and anti-oxidant supplements were found to have no effect on bladder cancer risk. The results of this study suggest that vitamin and anti-oxidant supplements may not exert any preventive effect on bladder cancer.

Research Summary Information

  • 2017
  • Park SJ, Myung SK, Lee Y, Lee YJ.
  • Department of Family Medicine, National Cancer Center, Goyang, Korea. Department of Family Medicine, Yonsei University Graduate School, Seoul, Korea. Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea. Molecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, Goyang, Korea. Center for Cancer Prevention and Detection, Hospital, National Cancer Center, Goyang, Korea. msk@ncc.re.kr. Department of Family Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea.
  • Yes, Free full text of study was found:
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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