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A Comprehensive Meta-Analysis on Dietary Flavonoid and Lignan Intake and Cancer Risk: Level of Evidence and Limitations

Creating more space for flavonoid-rich foods in our plate may help protect us from several types of cancer, including breast, lung, ovarian, colorectal, endometrial, stomach, and upper aerodigestive tract cancer.

The objective of this meta-analysis was to evaluate the correlation between dietary intake of flavonoids and lignans and cancer development risk. Researchers reviewed evidence from relevant studies on the subject. 

Researchers discovered habitual consumption of flavonoid-containing foods decreased an individual's likelihood of receiving a diagnosis of cancer of the lung, stomach, breast, colon, rectum, ovary, endometrium, and upper aerodigestive tract. This study suggests that individuals who want to minimize their risk of different types of cancer should add more foods packed with flavoniods to their diet.

Research Summary Information

  • 2017
  • Giuseppe Grosso, Justyna Godos, Rosa Lamuela-Raventos, Sumantra Ray, Agnieszka Micek, Andrzej Pajak, Salvatore Sciacca, Nicolantonio D'Orazio, Daniele Del Rio, Fabio Galvano
  • Integrated Cancer Registry of Catania-Messina-Siracusa-Enna, Azienda Ospedaliero-Universitaria Policlinico-Vittorio Emanuele, Catania, Italy. NNEdPro Global Centre for Nutrition and Health, St John's Innovation Centre, Cambridge, UK. Biomedical Research Center Network on Obesity and Nutrition (CIBERobn) Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain. Nutrition and Food Science Department-XaRTA, INSA, University of Barcelona, Barcelona, Spain. Medical Research Council (MRC) Human Nutrition Research Unit, Cambridge, UK. Department of Epidemiology and Population Studies, Jagiellonian University Medical College, Krakow, Poland. Department of Medical and Oral Sciences and Biotechnologies, University of Chieti, Chieti, Italy. Department of Food Science, University of Parma, Parma, Italy. Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
  • Yes, Free full text of study was found:
Does an apple a day keep the oncologist away?

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