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Is dietary nitrate/nitrite exposure a risk factor for development of thyroid abnormality? A systematic review and meta-analysis.
Frequent consumption of nitrite-containing foods may increase the risk of developing thyroid cancer.
This meta-analysis evaluated the association between high dietary exposure to nitrates and nitrites and the odds of developing thyroid abnormalities, such as hyperthyroidism, hypothyroidism, and thyroid carcinoma. Researchers conducted a meticulous meta-analysis on data extracted from relevant studies on the subject.
Researchers observed a significant elevation in likelihood of developing thyroid cancer among individuals who regularly consumed foods rich in nitrites. In contrast, no association was found between high dietary ingestion of foods packed with nitrates and hypothyroidism, hyperthyroidism, and thyroid cancer risk. The results of this study show that generous intake of nitrite-containing foods might be a risk factor for thyroid cancer.
Researchers observed a significant elevation in likelihood of developing thyroid cancer among individuals who regularly consumed foods rich in nitrites. In contrast, no association was found between high dietary ingestion of foods packed with nitrates and hypothyroidism, hyperthyroidism, and thyroid cancer risk. The results of this study show that generous intake of nitrite-containing foods might be a risk factor for thyroid cancer.
Research Summary Information
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2015
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Bahadoran Z, Mirmiran P, Ghasemi A, Kabir A, Azizi F, Hadaegh F.
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Nutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Ghasemi@endocrine.ac.ir. Minimally Invasive Surgery Research Center; Iran University of Medical Sciences, Tehran, Iran; Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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No, Free full text of study was not found.
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No. Source of funding disclosure not found
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No. Potential conflicts disclosure not found
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