High plasma cholesterol levels are associated with the presence of tendon pain and the development of abnormal tendon structure.

This study examined the relationship between blood cholesterol levels and tendon health. Researchers conducted a meta-analysis on 17 studies involving 2612 participants. They discovered that patients with tendon abnormalities or pain had reduced high-density lipoprotein cholesterol (HDL) but elevated triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL) levels in their blood. The result of this analysis shows that high serum concentrations of total cholesterol are associated with increased risk of tendon abnormalities or pain.