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Relationship between use of antidepressants and risk of fractures: a meta-analysis.

​Fracture is more likely to occur in antidepressant users than in non-users of these drugs.

The objective of this study was to investigate the association between antidepressant usage and the likelihood of suffering from bone fracture. Researchers reviewed data from 34 studies that revealed the detrimental effect of antidepressants on bone health.

Researchers observed that the tendency of having bone fracture was greater in antidepressant users than in non-users of these medications. According to this study, regular intake of antidepressant drugs was found to elevate the risk of hip, spinal, and non-vertebral fractures by 47%, 38%, and 42% respectively. In conclusion, the results of this meta-analysis suggest that antidepressant use may be a contributing factor to the development of bone fracture.

Research Summary Information

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