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Vegetarian diet, food substitution, and nonalcoholic fatty liver.

​Vegetarian diets may help prevent the development of non-alcoholic fatty liver disease (NAFLD).

This study examined the role of dietary patterns in the prevention and development of non-alcoholic fatty liver disease (NAFLD). Using validated food frequency questionnaires, researchers collated and analyzed data on the diets of 3400 vegetarians and non-vegetarians who were non-smokers and non-alcoholics and had no previous history of hepatitis B or C infection. The relative risk of fatty liver disease and the presence of liver fibrosis were determined in all the participants in this study using the non-alcoholic fatty liver disease score and ultrasonography respectively.

Researchers observed that vegetarians had lower risk of having non-alcoholic fatty liver disease and less severe liver fibrosis than non-vegetarians. According to this study, substituting a serving of soy with a serving of fish or meat and a serving of whole grains with refined grains and processed fruit juices increased the likelihood of developing non-alcoholic fatty liver disease by 12 – 13% and 3 – 12% respectively. The results of this study show that high intake of meat, fish, refined grains, and processed fruit juices may contribute to the development of non-alcoholic fatty liver disease.

Research Summary Information

  • 2018
  • Tina H Chiu, Ming-Nan Lin, Wen-Harn Pan, Yen-Ching Chen, Chin-Lon Lin
  • Department of Nutrition Therapy, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi; Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan Department of Family Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi; Department of Family Medicine, College of Medicine, Tzu Chi University, Hualien, Taiwan Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan Department of Internal Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation; Department of Internal Medicine, College of Medicine, Tzu Chi University, Hualien, Taiwan
  • Yes, Free full text of study was found:
  • No source of funding disclosure found
  • No potential conflicts disclosure found
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