Total cholesterol and cancer risk in a large prospective study in Korea.

Depending on the site, high consumption of cholesterol may increase cancer development risk in healthy adults.

This study investigated the relationship between cholesterol intake and cancer development risk. Using data obtained from the Korean National Health Insurance Corporation, researchers examined the diets of 1,189,719 Korean adults for 14 years.

Researchers discovered that high consumption of total cholesterol was associated with greater incidence of prostate and colon cancers in men and breast cancer in women. On the other hand, this study seemed to suggest that high total cholesterol intake diminished the risk of developing stomach, liver, and lung cancers in men and women. This analysis suggests that consuming large quantities of cholesterol may actually reduce the chances of developing liver, lung, and stomach cancers but is associated with elevated breast, prostate, and colon cancer risk.

Research Summary Information

  • 2011
  • Kitahara CM, Berrington de González A, Freedman ND, Huxley R, Mok Y, Jee SH, Samet JM.
  • National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
  • Yes, Free full text of study was found:
  • Source of funding disclosure found
  • Supported by Grant No. 10526 from Korean Seoul City Research and Grant No. 0920330 from the National Research and Development Program for Cancer Control, Ministry for Health, Welfare and Family Affairs, Republic of Korea. This study was also supported in part by the Intramural Research Program of the National Cancer Institute, National Institutes of Health.
  • No potential conflicts disclosure found
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