Statins and risk for new-onset diabetes mellitus: a real-world cohort study using a clinical research database.

Statin users are more likely to develop type 2 diabetes mellitus than non-users of this cholesterol-lowering drug.

Statins are a group of drugs that help reduce the level of low-density lipoprotein(LDL) cholesterol in the blood. This study assessed the association between statin therapy and the incidence of new-onset diabetes mellitus among Koreans. Researchers tracked data on the statin intake of 41,325 subjects and estimated the type 2 diabetes hazard ratio of each of the participant in this study. They observed a high prevalence of new-onset diabetes mellitus (NODM) among stain users. The results of this study support the hypothesis that people who take statins are at increased risk of developing type 2 diabetes mellitus.

Research Summary Information

  • 2016
  • Dukyong Yoon, Seung Soo Sheen, Sukhyang Lee, Yong Jun Choi,Rae Woong Park, and Hong-Seok Lim
  • Department of Biomedical Informatics Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine College of Pharmacy, Ajou University Department of Endocrinology and Metabolism Department of Cardiology, Ajou University School of Medicine, Suwon, Republic of Korea. Correspondence: Hong-Seok Lim, Department of Cardiology, Ajou University School of Medicine, 164 World Cup-ro, Yeongtong-gu, Suwon 16499, Republic of Korea (e-mail: rk.ca.uoja@milshdmac); Rae Woong Park, Department of Biomedical Informatics, Ajou University School of Medicine, 206 World Cup-ro, Yeongtong-gu, Suwon 16499, Republic of Korea (e-mail: rk.ca.uoja@satirev)
  • Yes, Free full text of study was found:
  • No source of funding disclosure found
  • No potential conflicts disclosure found
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