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Effects of low-fat diet on serum lipids in premenopausal and postmenopausal women: a meta-analysis of randomized controlled trials.

​A healthy cholesterol number is associated with premenopausal women on low-fat diets.

This study evaluated how low-fat diets affect the lipid profile of premenopausal and postmenopausal women. Researchers analyzed data extracted from 8 randomized clinical trials that investigated the effect of low-fat diets on plasma concentrations of triglycerides, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and total cholesterol in premenopausal and postmenopausal women.

Researchers discovered that increased intake of low-fat foods reduced the circulating levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and total cholesterol in premenopausal women but not in postmenopausal women. In contrast, low-fat diets did not increase or decrease the serum concentrations of triglycerides in both premenopausal and postmenopausal women. The results of this study indicate that a decrease in the consumption rates of fatty foods may help to reduce the concentrations of cholesterol floating in the blood of premenopausal women.

Research Summary Information

  • 2014
  • Wu L, Ma D, Walton-Moss B, He Z.
  • From the 1School of Nursing, Peking Union Medical College, Chinese Academy of Medical Science, Dongcheng District, Beijing, PR China; 2School of Nursing, Johns Hopkins University, Baltimore, MD; and 3School of Continuing Education, Peking Union Medical College, Chinese Academy of Medical Science, Dongcheng District, Beijing, PR China.
  • No, Free full text of study was not found.
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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