Effect of antioxidant vitamin supplementation on cardiovascular outcomes: a meta-analysis of randomized controlled trials.

The use of antioxidant vitamin supplements may not protect individuals against the stroke, myocardial infarction, and cardiovascular mortality.

This study evaluated the relationship between the use of antioxidant vitamin supplements, such as beta carotene, vitamin C and E supplements, and the occurrence of adverse cardiovascular events, such as stroke, myocardial infarction, and cardiac death by meta-analysis. Two hundred and ninety three (293) studies that examined one hundred and eighty thousand two hundred and nine (188,209) subjects were included in this meta-analysis. The team of researchers discovered that regular intake of antioxidant vitamin supplements had no significant effect on cardiovascular events, such as stroke, myocardial infarction, cardiac death, and total mortality risk. The findings of this meta-analysis reveal that supplementation with antioxidant vitamins may not affect the risk of suffering from adverse cardiovascular events, such as stroke, myocardial infarction, and death.

Research Summary Information

  • 2013
  • Ye Y, Li J, Yuan Z.
  • Department of Cardiovascular Surgery, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China.
  • Yes, Free full text of study was found:
  • No source of funding disclosure found
  • No potential conflicts disclosure found
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