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Citrus fruits intake and oral cancer risk: A systematic review and meta-analysis.

​A significant reduction in oral and pharyngeal cancer risk is associated with high consumption of citrus fruits.

The objective of this meta-analysis was to examine the association of dietary intake of citrus fruits with subsequent risk of oral and pharyngeal cancer. Data from 17 studies were evaluated for this meta-analysis.

Analysis of these data indicate that individuals who consumed the most amounts of citrus fruits had 50% lower risk of developing cancer of the mouth and pharynx than persons who ate little amounts or none of these types of fruits. In conclusion, the results of this meta-analysis demonstrate that fondness for citrus fruits may help to inhibit the formation, development, and spread of cancerous cells and tumors in the mouth and pharynx.

Research Summary Information

  • 2018
  • Cirmi S, Navarra M, Woodside JV, Cantwell MM
  • Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; Prof. Antonio Imbesi Foundation, Messina, Italy. Electronic address: scirmi@unime.it. Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy. Electronic address: mnavarra@unime.it. Nutrition and Metabolism Group, Institute for Global Food Security, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom. Electronic address: j.woodside@qub.ac.uk. Nutrition and Metabolism Group, Institute for Global Food Security, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom. Electronic address: m.cantwell@qub.ac.uk.
  • No, Free full text of study was not found.
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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